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249 words Introduction: 735 words Discussion: 1493 words d) ABBREVIATIONS: ABC, ATP-binding cassette transporter; ADO, adenosine; CFTR, cystic fibrosis transmembrane conductance regulator; EPAC, GTP-exchange protein activated by cAMP; FSK, forskolin; IBMX, 3-Isobutyl-1-methylxanthine; MEF, mouse embryonic fibroblast; MRP, multidrug resistant protein; PDE, cyclic nucleotide phosphodiesterase; PGE2, prostaglandin E2; PB, probenecid; PMEA, 9-(2-phosphonylmethoxyethyl)-adenine; RIA, radioimmunoassay; VASP, Vasodilator-stimulated phosphoprotein This article has not been copyedited and formatted. The final version may differ from this version. Molecular Pharmacology Fast Forward. Published on May 6, 2011 as DOI: 10.1124/mol.111.071134 at A PE T Jornals on M arch 1, 2017 m oharm .aspeurnals.org D ow nladed from